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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-361-3p
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples and matched adjacent, non-tumorous normal tissues; serum; RB cell lines Y79 and WERI-RB1
Methods qRT-PCR, transfection, MTT assay, CCK-8 assay, Western blot, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-361-3p functions as a tumor suppressor in the carcinogenesis and progression of RB by targeting SHH signaling.
PubMed ID 30679988
Year 2019
Title MicroRNA-361-3p regulates retinoblastoma cell proliferation and stemness by targeting hedgehog signaling.
Drug-related ncRNA NO

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